I'm currently working my way through this New Zealand series on Hulu called This Is Not My Life. The premise is that this guy wakes up in this futuristic society (so, yeah, science fiction) and doesn't know who or where he is, who these people in his house are, or pretty much anything about what is going on. It stars the guy who played Black Beard on OUaT (I'm about halfway through the show and just realized why he looks familiar!). If you liked the mystery of Wayward Pines, this might be a show for you.
I'm also doing the X Files rewatch (I don't remember most of these eps!), and I'm working on Sense8 and Daredevil when I have the brainpower to actually concentrate on them, and there are a few others I can't recall at the moment. But the main shows right now are This Is Not My Life and X Files.
ETA: And I was thinking about watching PLL because I love longform mysteries, and then I read the big reveal about who the central mysterious figure is, and I am never watching that show.